What is the endocannabinoid system?

When asked what the endocannabinoid system is, it must be answered that it is a system that exists in humans and some animals, such as dogs, cats and horses. This interesting system is composed of endocannabinoids and cannabinoid receptors, which work as if it were a key and a lock, in this regard:


They are long-chain polyunsaturated fatty acids derived from arachidonic acid. The most important are anandamide and 2-araquinodylglycerol and act as keys.

Endocannabinoid system

Cannabinoid receptors

These are cell membrane proteins and function as the lock for endocannabinoids, they are classified into cannabinoid receptor 1 and cannabinoid receptor 2, and are found in certain parts of the body.

That is, the CB1 receptors that are in the brain , also in the lungs, the liver and the kidneys and the CB2 receptors that are found throughout the body, it is worth knowing some key points about them.

Endocannabinoid system

How does the endocannabinoid system work?

The receptors are found on the surface of the cells , there they are attentive to external conditions and send the information about it, towards the interior of said cells. That is, the endocannabinoids activate the receptors and they are the only ones that can do it, they are the only key to the lock. 

From this communication or interaction several of the most important processes within the organism originate. It should be noted that endocannabinoids, as natural molecules that are produced within the body, have similarity to cannabinoids from the cannabis plant known as marijuana. 

In this case, THC or tetrahydrocannabinol activates the CB1 receptors generating the brain-raising effect, while CBD or cannabidiol activates the CB2 receptors producing a relaxing effect.

supports the endocannabinoid system

Does the endocannabinoid system work?

To know what the endocannabinoid system is, it is also key to know what its function is, basically it must regulate the different body systems in order to maintain balance for the correct functioning of the body.

This involves the pH levels in the blood, the blood sugar levels, the regulation of the amount in terms of water and minerals, the internal temperature, among many others. That is, the endocannabinoid system is responsible for adjusting most of the vital physiological functions and maintaining body homeostasis, ensuring that all systems work in a coordinated manner.

However, in some cases the endocannabinoid system is not capable on its own, giving rise to various ailments, that is when external cannabinoids begin to be used, for example those of cannabis and it can also be enhanced, there are several alternatives for this. In summary, the endocannabinoid system is vital to the body and its well-being and the little research that has been carried out is really promising.

what are the receptors of the endocannabinoid system

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cannabinoid system